Transcriptome and proteome profile analysis of the regulation of chicken ovarian development.

ABSTRACT: Ovarian development is a complex process, with early stages laying a crucial foundation for subsequent egg production. To better understand this developmental trajectory from early stages to the peak of egg production, this study employed transcriptomic and Tandem Mass Tag (TMT) proteomic analyses. These methods were used to compare gene and protein expression profiles in the ovaries of Taihe black-boned silky fowl (TBSF) at 20 weeks (20W) and 30 weeks (30W) of age, aiming to identify key regulatory mechanisms. Serum levels of follicle-stimulating hormone (FSH), luteinizing hormone (LH), estradiol (E2), and progesterone (P4) at 30 W were found to be higher than those at 20 W, indicating potential involvement of these hormones in ovarian maturation and the initiation of peak egg production.

SUBMITTER: Huang X 

PROVIDER: S-EPMC12169740 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature