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Sex differences in outcomes after endovascular therapy with prior antiplatelet use: A study from the EVA-TRISP registry.


ABSTRACT:

Introduction

This study assessed sex differences in outcomes after mechanical thrombectomy (MT) with prior antiplatelet use using the EVA-TRISP multinational registry.

Patients and methods

A cohort of consecutive patients (2015-2023) treated with MT was analysed by sex and prior antiplatelet use in multivariable logistic regression models. Primary outcomes were in-hospital symptomatic intracranial haemorrhage (sICH) and the 3-month modified Rankin Scale (mRS) score.

Results

Among 7472 patients (47.9% females, older than males: 77 vs 72 years, p < 0.0001), sICH rates were similar (females 4.6%, males 4.4%, p = 0.405). The odds of sICH were not influenced by sex (adjusted odds ratio, aOR, 0.99, 95% confidence interval, CI, 0.77-1.28) or prior antiplatelet

SUBMITTER: Noseda R 

PROVIDER: S-EPMC12170539 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature