Transcranial magnetic stimulation measures of corticospinal excitability in Black and Hispanic/Latino people with painful peripheral neuropathy.

ABSTRACT:

Introduction

This study aims to provide preliminary descriptive data on transcranial magnetic stimulation (TMS) measures obtained in Black and Hispanic/Latino individuals with chronic painful peripheral neuropathy (PN), including those with chemotherapy-induced peripheral neuropathy (CIPN) and diabetic neuropathy (DN). Both CIPN and DN share similar neuropathic symptoms and underlying physiological mechanisms, in particular altered central nervous system processing. TMS is a non-invasive technique that can assess corticospinal excitability and the function of GABAergic and glutamatergic pathways, potentially serving as a diagnostic or prognostic tool for PN.

Methods

This study utilized data from a pilot randomized sham-controlled trial that tested the impact of patient educa

SUBMITTER: Wong ML 

PROVIDER: S-EPMC12171121 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature