The role of cysteine-rich protein in enhancing mandarivirus infectivity and pathogenicity.

ABSTRACT: Mandariviruses pose a significant threat to the citrus industry due to their diverse transmission modes and high pathogenicity. However, the pathogenicity mechanisms of mandariviruses remain largely unknown, especially as there is a complete lack of understanding regarding the function of the cysteine-rich proteins (CRPs) encoded by mandariviruses during infection. In this study, ectopic expression of two mandarivirus CRPs from citrus yellow mottle-associated virus (CiYMaV) and citrus yellow vein clearing virus (CYVCV) using a potato virus X vector resulted in severe symptoms and increased viral accumulation in Nicotiana benthamiana. CiYMaV CRP induced cell death in N. benthamiana leaves, with the zinc finger motif identified as the critical region responsible for this induct

SUBMITTER: Wu J 

PROVIDER: S-EPMC12172455 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature