Ultrahypofractionated radiotherapy for localised prostate cancer: The impact of daily MRI-guided adaptive radiotherapy on delivered dose.

ABSTRACT:

Introduction

Magnetic resonance image-guided adaptive radiotherapy (MRIgART) reduces uncertainties by correcting for day-to-day target and organ-at-risk deformation and motion. This is the first study to examine the dosimetric impact of MRIgART for ultrahypofractionated prostate cancer treatment, compared to standard-of-care image-guided non-adapted radiotherapy.

Methods

Twenty patients with localised prostate cancer, who received ultrahypofractionated MRIgART on the Unity MR linac (Elekta, Sweden) were retrospectively analysed. Online daily MRI was acquired for replanning (MRI_session) and a second for position verification before treatment (MRI_verification). To compare delivered dose with and without adaptation, three plans were generated offline per f

SUBMITTER: Alexander SE 

PROVIDER: S-EPMC12173759 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature