Impact of paediatric antimicrobial stewardship program in haematogenous bone and joint infections.

ABSTRACT: Antimicrobial stewardship programs (ASP) reduce the inappropriate use of antimicrobial agents. Traditionally, paediatric osteoarticular infections have been treated with prolonged intravenous antibiotics; however, evidence suggests that shorter intravenous therapy followed by oral narrow-spectrum antibiotics is effective. The aim of this study is to assess the impact of an ASP on the treatment of acute haematogenous bone and joint infections (AH-BJI) in children.We performed a single-centre quasi-experimental study comparing antibiotic use in paediatric [0-18 years] inpatients with AH-BJI before (2015-2016 period 1 [P1]) and after (2017-june 2023 period 2 [P2]) the implementation of a multifaceted hospital ASP with post-prescription review with feedback as the primary strategy. ASP also pr

SUBMITTER: Font A 

PROVIDER: S-EPMC12174213 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature