Exploring the evolutionary journey of the lumpy skin disease virus through the phylogenetic and phylo-geo network analysis.

ABSTRACT:

Introduction

Lumpy Skin Disease Virus (LSDV), an emerging pathogen from the Capripoxvirus genus, continues to challenge global livestock health with its expanding host range and genetic adaptability.

Materials and methods

In this study, we report the first isolation and whole genome sequencing of LSDV from Bos frontalis, a semi-domesticated bovine species native to Northeast India, along with the assembly of an isolate from cattle.

Results

Time to the Most Recent Common Ancestor (TMRCA) estimates support a relatively recent common origin for Indian strains, pointing to ongoing virus circulation and regional adaptation. The maximum likelihood phylogenetic tree of the whole genome and G protein-coupled chemokine receptor (GPCR) gene further demonstrated the clust

SUBMITTER: Bayyappa MRG 

PROVIDER: S-EPMC12174415 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature