Mechanistic insights into cadmium-related premature aging in <i>Drosophila</i> model.

ABSTRACT: The intricate and multifaceted relationship between environmental pollutants, particularly heavy metals such as cadmium, and human health has been extensively documented, with a significant focus on their neurotoxic effects. Notably, the connection between cadmium exposure and Alzheimer's disease is becoming increasingly evident, prompting a deeper investigation into the underlying mechanisms at play. Despite the growing body of evidence linking cadmium to neurodegeneration and although harmful molecular activities of cadmium in cells have been demonstrated, the precise molecular mechanism induced by this toxic metal within neuronal cells remains largely enigmatic. This study aims to shed light on these mechanistic processes by utilizing Drosophila melanogaster, a widely recognized

SUBMITTER: De Donno MD 

PROVIDER: S-EPMC12174419 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature