Relationship Between Systemic and Cerebral Microdialysate Glucose in Patients With Severe Acute Brain Injury-A Retrospective Study.

ABSTRACT:

Background

Markers of cerebral metabolism measured by microdialysis (CMD) may warn clinicians of impending neuroworsening in patients with severe acute brain injury. This retrospective study investigated the relationship between systemic glucose levels and microdialysate glucose (CMD-glucose) in patients with severe traumatic brain injury (TBI) or aneurysmal subarachnoid haemorrhage (SAH).

Methods

We retrospectively investigated patients who underwent CMD. Linear regression and correlation analysis between temporally matched values of systemic and CMD-glucose were performed. Disease severity was dichotomized using the Glasgow Coma Scale score (GCS) at admission, and patient outcome at 6 months was dichotomized using the modified Rankin Scale.

Results

Data was availabl

SUBMITTER: Fenger AW 

PROVIDER: S-EPMC12174490 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature