<i>In vitro</i> determination of essential genes required by <i>Streptococcus uberis</i> to grow in a complex biological media relating to intramammary infection.

ABSTRACT: Streptococcus uberis is a leading cause of bovine mastitis, a disease of significant economic impact to the dairy industry. Understanding the genetic factors essential for bacterial survival in milk and during intramammary infection is crucial for developing effective interventions and reducing the reliance on antimicrobials. Some studies have looked at how certain genes affect the growth and spread of S. uberis in milk, but they have mostly ignored the impact of inflammation and increased blood vessel permeability.Cultures in milk containing serum subsequently exhibited accelerated growth rate and yield in proportion to the concentration of serum, potentially highlighting a role in bacterial proliferation. Using high-throughput transposon insertion sequencing, genes essentia

SUBMITTER: Blanchard AM 

PROVIDER: S-EPMC12174587 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature