Advanced cardiac magnetic resonance imaging for assessment of obstructive coronary artery disease-ADVOCATE-CMR study rationale and design.

ABSTRACT:

Background

First-pass stress-perfusion cardiovascular magnetic resonance (CMR) imaging is the guidelines-recommended non-invasive test for the detection of obstructive coronary artery disease (CAD). Recently developed quantitative perfusion CMR (QP CMR) allows quantification of myocardial blood flow. Moreover, the latest developments established several methods of CAD assessment without the need for a contrast agent, including stress T1 mapping reactivity (∆T1) and oxygenation-sensitive CMR (OS-CMR). These methods might eliminate the need for contrast administration in clinical practice, reducing time, invasiveness, and costs, thereby simplifying the evaluation of patients with suspected obstructive CAD. The ADVOCATE-CMR study aims to validate QP CMR, ∆T1, and OS-CMR imaging agains

SUBMITTER: Borodzicz-Jazdzyk S 

PROVIDER: S-EPMC12175715 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature