PRESERVE: adding variable flip-angle excitation to transverse relaxation-optimized NMR spectroscopy.

ABSTRACT: We introduce the "Polarization Restoring Excitation SEquence foR Versatile Experiments" (PRESERVE) pulse sequence element, allowing variable flip-angle adjustment in 2D 1 H- 15 N and 1 H- 13 C transverse-relaxation-optimized-spectroscopy (TROSY)-type correlation experiments. PRESERVE-TROSY exploits a remarkable array of up to nine orthogonal coherence-transfer pathways, showcasing the remarkable potential of spin manipulations achievable through the design and optimization of nuclear magnetic resonance (NMR) pulse sequences.

SUBMITTER: Brutscher B 

PROVIDER: S-EPMC12178132 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature