A decade of Benzodiazepine and Z-drug use in Hong Kong: a longitudinal study.

ABSTRACT:

Background

Concerns are growing about the long-term use of benzodiazepines (BZDs) and non-benzodiazepines (Z-drugs) due to adverse effects such as drug tolerance, dependence, cognitive dysfunction, and falls, particularly in the elderly. This study aims to understand thorough prescribing patterns of BZDs and Z-drugs across age groups in clinical settings of Hong Kong, especially the long-term prescriptions.

Methods

Using territory-wide electronic health record data from Hong Kong (2014-2023), we analysed the prevalence, incidence, and duration of BZD and Z-drug prescriptions in adults. Long-term use was defined as prescriptions exceeding 90 days. Joinpoint regression models assessed trend changes, focusing on four age groups: 18-25, 26-49, 50-64, and ≥65. Psychiatric diagnos

SUBMITTER: Lee KJ 

PROVIDER: S-EPMC12178920 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature