Influence of a six-month home-based individualized physical activity intervention on carotid plaque instability measured by magnetic resonance imaging: a randomized controlled clinical trial.

ABSTRACT:

Background

Management of asymptomatic patients with carotid atherosclerotic plaque is still debated. Intraplaque haemorrhage measured by magnetic resonance imaging is the best in-vivo indicator of plaque instability and ischaemic risk. A cross-sectional study reported that physical activity was associated with lower prevalence of carotid intraplaque haemorrhage. The aim of this trial was to determine the influence of a physical activity intervention on plaque instability in asymptomatic patients with carotid stenosis.

Methods

Physical Activity and Carotid Atherosclerotic Plaque haemorrhage is a randomized clinical trial (ID-RCB:2019-A01543-54/SI:19.06.21.40640; registered on clinicaltrials.govNCT04053166). Patients were enrolled at University Hospital of Lyon,

SUBMITTER: Mura M 

PROVIDER: S-EPMC12179388 | biostudies-literature | 2025 May

REPOSITORIES: biostudies-literature