Interplay between bacterial clones and plasmids in the spread of <i>bla</i> <sub>SHV-12</sub>- and <i>bla</i> <sub>CTX-M-14</sub>-carrying <i>Escherichia coli</i> from the livestock environment.
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ABSTRACT: To better understand the role of broiler and pig farms as reservoirs and disseminating vehicles of Extended-Spectrum β-lactamase (ESBL)-producing Escherichia coli (Ec), we performed a phylogenomic and plasmid analysis with a holistic view (human-animal-environmental interface). Here, we selected 15 ESBL-Ec recovered from the slurry, manure or air of pig (n = 7) and broiler farms (n = 8) in La Rioja (Spain) for Whole-Genome Sequencing (WGS). ESBL-E. coli isolates from a broiler farm (BF) all carried the bla SHV-12 gene associated with ST68/ST117/ST770/ST1684 and the new genetic lineage ST15985. On the contrary, all those from a pig farm (PF) carried the bla CTX-M-14 gene associated with ST453/ST542/ST4038, and 6/7 isolates co-h
SUBMITTER: Martinez-Alvarez S
PROVIDER: S-EPMC12179637 | biostudies-literature | 2025 Jun
REPOSITORIES: biostudies-literature
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