Mediating Effects of Systemic Inflammation on the Association Between Body Roundness Index and Periodontitis in US Adults.

ABSTRACT:

Introduction and aim

Periodontitis is a highly prevalent chronic inflammatory disease affecting periodontal tissues. While the Body Roundness Index (BRI), has emerged as a novel anthropometric measure for evaluating obesity-related health risks, its relationship with periodontal health remains unexplored. Although systemic inflammation is recognized as a key role in both obesity and periodontitis. However, whether BRI affects periodontitis, the mediating role of systemic inflammation in BRI-related periodontitis has not been elucidated.

Materials and methods

Data were derived from the National Health and Nutrition Examination Survey (NHANES) 2009-2014, comprising 8415 participants aged ≥18 years. We analysed BRI's correlation with periodontal disease using binary logistic re

SUBMITTER: Zhang H 

PROVIDER: S-EPMC12180997 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature