Experimental Usutu virus infection in Eurasian blackbirds (Turdus merula).

ABSTRACT: Usutu virus (USUV) is a zoonotic arbovirus causing disease in wild birds and humans. Eurasian blackbirds (Turdus merula) are highly susceptible to infection, developing severe lesions with high mortality rates during outbreaks. The pathogenesis and clinical course of the acute disease in birds are not known. Therefore, six blackbirds were infected with two USUV lineages (Africa 3 and Europe 3). The blackbirds were monitored for clinical signs of disease and activity levels and were sampled for virus detection. All infected blackbirds showed severe disease after 4 to 7 days, with no significant differences between the lineages. Reaching a humane endpoint, the blackbirds were euthanized, and tissue samples were collected for histopathology and virology. At histopathology, lesions were seen i

SUBMITTER: Agliani G 

PROVIDER: S-EPMC12181337 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature