Weighted Vest Use or Resistance Exercise to Offset Weight Loss-Associated Bone Loss in Older Adults: A Randomized Clinical Trial.

ABSTRACT:

Importance

Weight loss (WL) in older adults is associated with bone loss, increasing the risk of fracture. Because skeletal tissue is responsive to mechanical stress, replacing lost weight externally may be an innovative way to minimize WL-associated bone loss in this population.

Objective

To examine the effect of 12 months of weighted vest use during WL on indicators of bone health compared with WL alone and WL plus resistance training (RT).

Design, setting, and participants

This single-blind, 12-month randomized clinical trial of older adults living with obesity was conducted at an academic medical center from September 1, 2019, to April 30, 2024.

Interventions

WL (caloric restriction targeting 10% WL with adequate calcium, vitamin D, and protein), WL plus we

SUBMITTER: Beavers KM 

PROVIDER: S-EPMC12181796 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature