Myocardial native T1 and extracellular volume measurements at 5T: Feasibility study and initial experience.

ABSTRACT:

Background

T1 mapping is a robust and highly reproducible technique for quantitative assessment of cardiomyopathy. The aim of this study is to investigate the feasibility of 5T myocardial T1 mapping and to establish preliminary reference values for myocardial T1 at 5T.

Methods

Twenty-eight healthy volunteers (median age, 42 [interquartile range (IQR): 29-54] years; 14 male) and 11 patients (median age, 44 [IQR: 34-51] years; 7 male) underwent cardiovascular magnetic resonance at 5T. T1 mapping was acquired using a motion-corrected modified Look-Locker inversion recovery sequence [5(3)3 scheme for pre-contrast, (4(1)3(1)2) scheme for post-contrast] in three short-axis planes (base, middle, and apex). T1 values were quantified per segment, per slice, and globally.

Results</

SUBMITTER: Guo Y 

PROVIDER: S-EPMC12182820 | biostudies-literature | 2025 Summer

REPOSITORIES: biostudies-literature