Impact of transapical beating-heart septal myectomy on left atrial remodeling and atrioventricular coupling in hypertrophic obstructive cardiomyopathy.

ABSTRACT:

Background

Assessment of left atrial (LA) functional strain and atrioventricular coupling is increasingly recognized as critical in patients with hypertrophic obstructive cardiomyopathy (HOCM), associated with adverse atrial remodeling and malignant arrhythmia. The effect of transapical beating-heart septal myectomy (TA-BSM) on the improvement of LA function and atrioventricular coupling remains uncertain.

Methods

The patients with HOCM who underwent TA-BSM in Tongji Hospital between April 2022 and October 2023 were prospectively investigated. The LA structure parameters (diameters and volumes), functional parameters (total LA emptying fraction [LAEF], total strain [εs], peak positive strain rate [SRs], passive LAEF, passive strain [εe], peak early negative strain rate [SRe]

SUBMITTER: Zhao Y 

PROVIDER: S-EPMC12182824 | biostudies-literature | 2025 Summer

REPOSITORIES: biostudies-literature