Abnormalities of Hippocampal Subfields in Individuals With Acute Carbon Monoxide Poisoning.

ABSTRACT:

Objective

To investigate alterations in hippocampal subfields in patients with acute carbon monoxide poisoning (ACMP) and explore their relationship with neurocognitive function.

Materials and methods

Forty-seven ACMP patients and 29 age- and sex-matched healthy controls (HCs) were recruited. All ACMP patients underwent carboxyhemoglobin (COHb) assessment at admission and acquired MRI scans within 3 days post-exposure. Cognitive functions were assessed using the mini-mental state examination (MMSE) and Montreal Cognitive Assessment (MoCA), and activities of daily living were evaluated using the Functional Independence Measure (FIM) and Barthel Index (BI). Differences in hippocampal volume between groups were analyzed using Analysis of Covariance (ANCOVA), and correlations wi

SUBMITTER: Tang M 

PROVIDER: S-EPMC12183523 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature