Comprehensive analysis of <i>Enterococcus</i> spp. from two European healthy infant cohorts shows stable genomic traits including antimicrobial resistance (AMR).

ABSTRACT: Enterococcus spp. some of which are pathogenic, are common gut microbiota members, including also infants. Infants may be more susceptible to Enterococcus due to their developing gut ecosystems. It is unclear whether antibiotic resistance genes (ARGs) and certain genomic traits in enterococci are restricted to the human subpopulation or more widespread. Furthermore, the correlation between these traits and geographic variation is poorly understood. Therefore, we sequenced 100 strains isolated from full-term healthy infants' fecal samples from two geographically distant European cohorts (MAMI in Spain and LucKi from the Netherlands) to explore the diversity of Enterococcus spp. within the infant's gut microbiome and assess cohort-specific traits such as ARGs. Most isola

SUBMITTER: Saeed MH 

PROVIDER: S-EPMC12184193 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature