Longitudinal trajectories of brain development from infancy to school age and their relationship with literacy development.

ABSTRACT: Reading is one of the most complex skills that we utilize daily, and it involves the early development and interaction of various lower-level subskills, including phonological processing and oral language. These subskills recruit brain structures, which begin to develop long before the skill manifests and exhibit rapid development during infancy. However, how longitudinal trajectories of early brain development in these structures support long-term acquisition of literacy subskills and subsequent reading is unclear. Children underwent structural and diffusion MRI scanning at multiple timepoints between infancy and second grade and were tested for literacy subskills in preschool and decoding and word reading in early elementary school. We developed and implemented a reproducible pipeline to

SUBMITTER: Turesky TK 

PROVIDER: S-EPMC12184337 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature