Biparental inheritance of germline-specific chromosomes in the sea lamprey and their roles in oocytes.

ABSTRACT: Many eukaryotic species undergo programmed elimination of specific chromosomes during embryogenesis, typically retaining these chromosomes only in their germ cells. In some species, programmatic elimination of GRCs, or sex chromosomes, also occurs in a sex-specific manner, with specific chromosomes being transmitted or eliminated by only one sex. As such, these chromosomes provide a unique perspective on the evolution of gene functions that are advantageous to the germline and genetic tradeoffs between somatic vs germline or oocyte vs sperm biology. While GRCs have been extensively characterized in male sea lampreys (Petromyzon marinus), the status of GRCs in females has not yet been resolved, though it has been hypothesized that male-specific expression/transmission of these chromo

SUBMITTER: Timoshevskiy VA 

PROVIDER: S-EPMC12184396 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature