Role of Heart Rate Recovery in Chronic Heart Failure: Results From the MyoVasc Study.

ABSTRACT:

Background

Cardiac autonomic dysfunction is associated with heart failure (HF). Reduced heart rate recovery (HRR) indicates impaired parasympathetic reactivation after physical activity. Heart rate recovery 60 seconds after peak effort (HRR₆₀) is linked to autonomic dysfunction, but data on its relevance across HF phenotypes are scarce. This study aimed to identify clinical determinants of HRR₆₀ in an HF cohort and assess its relationship with clinical outcomes.

Methods

Data from the MyoVasc study (NCT04064450; N=3289) were analyzed. Participants underwent standardized clinical phenotyping including cardiopulmonary exercise testing. HRR₆₀ was defined as the heart rate decline 60 seconds after exercise termination. Clinical determinants of HRR

SUBMITTER: Velmeden D 

PROVIDER: S-EPMC12184589 | biostudies-literature | 2025 May

REPOSITORIES: biostudies-literature