Identification of candidate genes for reproductive traits in Xinjiang sheep breeds based on genomic structural variation.

ABSTRACT: Reproductive traits are among the most important economic characteristics in sheep farming. Structural variations (SVs) are extensively distributed across sheep genomes and can directly or indirectly affect gene expression through a variety of mechanisms, leading to phenotypic variation among individuals or breeds. In this study, we characterized genomic SVs and identified candidate genes related to germplasm traits in seven sheep breeds. Based on the genome sequences of 73 ewes, SVs were detected using Delly, Lumpy, and Manta software tools, and the results were integrated using SURVIVOR software, leading to the identification of 107,166 SVs. The proportions of deletions, duplications, insertions, inversions, and translocations were 48.39, 38.41, 6.96, 6.22, and 0.03%, respectively. Regar

SUBMITTER: Li J 

PROVIDER: S-EPMC12184774 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature