Feasibility and acceptability of GeneXpert MTB/XDR implementation among healthcare workers in three low-middle income African countries.

ABSTRACT:

Background

Xpert MTB/XDR (Xpert-XDR) testing can significantly shorten time to initiating appropriate drug-resistant tuberculosis (DR-TB) treatment, but its introduction may impact laboratory workflow, especially in laboratories not currently performing drug susceptibility testing. This study evaluated the feasibility and acceptability of implementing the Xpert-XDR for rapid triage and selection of all-oral regimens for DR-TB.

Method

This was a multi-country, multi-site qualitative study conducted between July and November 2023, as part of the larger TriAD (Triage test for All oral DR TB drugs) study implemented in South Africa, Ethiopia, and Nigeria. We conducted semi-structured in-depth interviews with clinicians, nurses and laboratory staff at each study site until themat

SUBMITTER: Keller S 

PROVIDER: S-EPMC12186877 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature