Cross-field strength and multi-vendor reliability of MagDensity for MRI-based quantitative breast density analysis.

ABSTRACT:

Purpose

Breast density (BD) is a significant risk factor for breast cancer, yet current assessment methods lack automation, quantification, and cross-platform consistency. This study aims to evaluate the reliability and cross-platform consistency of MagDensity, a novel magnetic resonance imaging (MRI)-based quantitative BD measure, across different imaging platforms.

Methods

Ten healthy volunteers participated in this prospective study, undergoing fat-water MRI scans on three scanners: 3T Siemens Prisma, 3T Siemens Biograph mMR, and 1.5T GE Signa. Great effort was made to schedule all scans within a narrow three-hour window on the same day to minimize any potential intra- or inter-day variations, requiring substantial logistical coordination. BD was assessed using the MagDen

SUBMITTER: Ying J 

PROVIDER: S-EPMC12186934 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature