Proteomic analysis of outer membrane vesicles derived from the type A5 Strain of <i>Mannheimia haemolytica</i>.

ABSTRACT: Mannheimia haemolytica (M. haemolytica) cause mastitis in sheep, acute sepsis in newborn lambs, and co-infections with various pathogens, leading to bovine respiratory disease syndrome (BRDS), these infections have resulted in significant economic losses to both domestic and international farming industries. An in-depth understanding of the pathogenic mechanisms of M. haemolytica is crucial for the prevention and control of this disease. Outer membrane vesicles (OMVs) play a vital role in bacterial pathogenesis, serving as key mediators of interactions between Gram-negative bacteria and their hosts. However, the specific role of OMVs in the pathogenic process of M. haemolytica remains poorly understood. To address this, we isolated OMVs from the Mannheimia ha

SUBMITTER: Shang K 

PROVIDER: S-EPMC12187688 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature