Association of Albuminuria Within the Normoalbuminuric Range With All-Cause Mortality in People With Type 2 Diabetes.

ABSTRACT:

Aims

To investigate the independent association of albuminuria within the normoalbuminuric range with all-cause mortality in normoalbuminuric people with type 2 diabetes with and without chronic kidney disease (CKD).

Materials and methods

This observational, prospective, multicentre, cohort study enroled 15,773 individuals with type 2 diabetes in 2006-2008. At baseline, albumin excretion rate (AER) and estimated glomerular filtration rate (eGFR) were assessed together with cardiometabolic risk profile, treatments, complications, and comorbidities. All-cause mortality was verified on 31 October 2015.

Results

Of the 15,656 participants (99.3%) with valid information on vital status, 11,460 (71.2%) were normoalbuminuric, 9984 (87.1%) without and 1476 (12.9%) with CKD. No

SUBMITTER: Garofolo M 

PROVIDER: S-EPMC12188507 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature