Clinician Recommendation for Hereditary Genetic Testing in Participants at Increased Risk for Hereditary Cancer.

ABSTRACT: Background: Despite clinical utility in managing hereditary cancers, genetic testing (GT) remains underutilized. While barriers include knowledge gaps and cost, clinician recommendation is a major driver of GT uptake, with rates varying by cancer type and family cancer history documentation. Methods: Adult participants (≥18 years) were recruited through multiple sources to complete a cancer family history survey for a larger intervention trial. Participants with personal or family history indicating increased hereditary cancer risk who had not undergone GT (N = 3001) were invited to complete a baseline survey. Multivariable logistic regression was used to analyze associations between demographics and cancer history by receipt of a clinician recommendation for GT. Results:<

SUBMITTER: Delacroix E 

PROVIDER: S-EPMC12190242 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature