Ablative Techniques for Lung Metastases: Patient Selection and Outcomes Following Treatment with Stereotactic Radiotherapy or Radiofrequency Ablation.

ABSTRACT: Stereotactic radiotherapy (SBRT) and radiofrequency ablation (RFA) are common ablative techniques for lung metastases. A retrospective review of all patients treated with either modality at a single institution between 2011 and 2019 was conducted. Baseline characteristics and outcomes were compared. Local and distant progression, and overall survival were estimated using the Kaplan-Meier method. Univariable analysis was carried out using Cox regression; this was followed by multivariable modelling. In total, 106 patients treated with RFA and 70 treated with SBRT were identified. Tumours treated with SBRT were larger (median size 18 mm vs. 11 mm) and primarily oligometastatic (91.4% vs. 20%). Median progression-free survival (PFS) was 12.5 months for SBRT and 7.9 months for RFA (p =

SUBMITTER: Pang JWS 

PROVIDER: S-EPMC12191657 | biostudies-literature | 2025 May

REPOSITORIES: biostudies-literature