Associations between genetic HPV 16 diversity and cervical cancer prognosis.

ABSTRACT:

Introduction

Cervical cancer (CC) arises as a result of chronic and persistent female infection by different oncogenic human papillomaviruses (HPV). The incidence of this disease is still high in developing countries, such as Brazil, where diagnosis is often made in advanced stages. HPV 16 is the most common Papillomavirus genotype in CC worldwide. Studies regarding the association of different HPV 16 lineages with overall and disease-free CC survival rates can contribute to further understanding the behavior of different HPV 16 lineages concerning the prognosis of CC cases.

Objective

To assess the CC prognosis of patients treated in a Brazilian institution concerning HPV16 lineages.

Methods

Data were obtained from a prospective cohort of 334 patients with CC recruite

SUBMITTER: Patury P 

PROVIDER: S-EPMC12193069 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature