Lanka virus, a Mus booduga-borne orthohantavirus infection-associated febrile illness in Sri Lanka.

ABSTRACT:

Background

In Sri Lanka, a high seroprevalence of antibodies against hantaviruses was reported in communities affected by chronic kidney disease of unknown etiology (CKDu). Recently, two rodent-borne hantaviruses, Lanka virus and Anjozorobe virus, were identified in these areas. However, it is unclear which virus is the source of infection in humans, and its pathogenicity is unknown.

Methodology/principal findings

A total of 181 sera from febrile patients from two CKDu-endemic regions, Girandurukotte and Polonnaruwa, were examined and Lanka virus genome was detected in two IgM-positive febrile patients. Of 76 serum samples from patients with fever of unknown etiology collected during 2016 examined to identify hantavirus genomes, antibodies, and serotypes, 10 were IgG-positiv

SUBMITTER: Muthusinghe DS 

PROVIDER: S-EPMC12193775 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature