The Growth, Pathogenesis, and Secondary Metabolism of <i>Fusarium verticillioides</i> Are Epigenetically Modulated by Putative Heterochromatin Protein 1 (FvHP1).

ABSTRACT: Fusarium verticillioides is a globally prevalent phytopathogenic fungus responsible for multiple diseases in maize and a major producer of the mycotoxin fumonisin B1 (FB1), a highly toxic fungal secondary metabolite (FSM). The histone code, which includes reversible modifications such as acetylation and methylation, plays a critical role in regulating chromatin structure and gene expression. In fungi, di- and tri-methylation of histone H3 at lysine 9 (H3K9me2/3) serves as a key epigenetic mark associated with heterochromatin formation and transcriptional repression. In this study, we identified and characterized a putative heterochromatin protein 1 (HP1) family member in F. verticillioides, designated FvHP1, based on conserved domain architecture and phylogenetic analyses. Fv

SUBMITTER: Jacquat AG 

PROVIDER: S-EPMC12194461 | biostudies-literature | 2025 May

REPOSITORIES: biostudies-literature