Genomic Diversity and Antibiotic Resistance of <i>Escherichia coli</i> and <i>Salmonella</i> from Poultry Farms in Oyo State, Nigeria.

ABSTRACT: Livestock are a source of zoonotic pathogens and bacteria harbouring antimicrobial resistance (AMR) that can pose a threat to public health. This study assessed the burden of antimicrobial resistance (AMR) and genomic diversity of Salmonella and Escherichia coli at 25 poultry farms in Oyo State, Nigeria. The farm-level occurrence of Salmonella was 48%, with 12 serovars identified, including S. Kentucky Sequence Type 198. Notably, 70% of Salmonella isolates were resistant to fluoroquinolones, and multidrug resistance was observed in S. Kentucky and S. Derby. The study also found a 52% farm-level occurrence of extended-spectrum beta-lactamase-producing E. coli, with four bla_CTX-M variants detected (bla_CTX-M-15, bla_CTX-M-27,

SUBMITTER: Adetunji VO 

PROVIDER: S-EPMC12195307 | biostudies-literature | 2025 May

REPOSITORIES: biostudies-literature