Later eating timing in relation to an individual internal clock is associated with lower insulin sensitivity and affected by genetic factors.

ABSTRACT:

Background

Although the contribution of the circadian clock to metabolic regulation is widely recognized, the role of eating timing in glucose metabolism and diabetes risk remains insufficiently studied. This study aimed (i) to investigate the link between the eating timing pattern relative to individual clock and glucose homoeostasis and (ii) to explore the contribution of genetic and environmental factors to eating timing parameters.

Methods

In 92 adult twins (NCT01631123), glycaemic traits were assessed using the oral glucose tolerance test. Parameters of eating timing pattern (eating timing itself, daily calorie distribution, and eating frequency) were extracted from five-day food records. Caloric midpoint defined as the time point at which 50% of daily calories are cons

SUBMITTER: Vahlhaus J 

PROVIDER: S-EPMC12197976 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature