Information processing speed modulation by electrical brain stimulation in multiple sclerosis: towards individually tailored protocols.

ABSTRACT: Information processing speed is a core cognitive process, highly relevant in everyday life and the most frequent and disabling cognitive symptom in patients with relapsing multiple sclerosis. Correlational evidence from brain imaging suggests involvement of the superior parietal lobe in the speed component of information processing, thereby providing a neurobiological foundation for neuromodulatory interventions. By using regionally specific, focalized transcranial direct current stimulation (tDCS) in healthy individuals and patients with relapsing multiple sclerosis, we provide causal evidence for superior parietal lobe involvement in information processing speed and identified a clinically relevant predictor of tDCS response in patients with relapsing multiple sclerosis. The study employ

SUBMITTER: Riemann S 

PROVIDER: S-EPMC12198773 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature