Identification of new candidate genes affecting drip loss in pigs based on genomics and transcriptomics data.

ABSTRACT: Drip loss (DL) is a crucial trait for evaluating muscle quality in pigs. In this study, Chinese Suhuai pigs with DL records were genotyped using the Neogen GGP Porcine 80 K single-nucleotide polymorphism (SNP) array to identify quantitative trait locus (QTL) affecting DL and dissect candidate genes for this trait. The SNP-chip data was imputed to the level of whole-genome sequence (iWGS). Through genome-wide association studies (GWAS) based on iWGS data, significant SNPs were detected on Sus scrofa chromosomes (SSC) 4, SSC13, and SSC14 for DL, involving 37 candidate genes such as AACS, CRB4, and OXSM. Notably, 3 QTL regions (SSC4, SSC13, and SSC14) were newly identified in this study, which were SSC4: 65.2 to 66.1 Mb, SSC13:12.46 to 12.48 Mb and SSC14: 20.7 to 20.9 Mb respectively. Additio

SUBMITTER: Yu J 

PROVIDER: S-EPMC12198960 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature