Association Between Changes in Body Composition and Physical Function After Intensive Behavioral Weight-loss Intervention: A Look AHEAD Trial Subgroup Analysis.

ABSTRACT:

Background

Intentional weight loss improves physical function among older adults with obesity, despite the associated lean mass loss. However, prior studies have not assessed the impacts of weight loss on physical function and body composition among older adults with type 2 diabetes mellitus and obesity, a population at high risk for sarcopenia and functional decline. Our objective was to examine differences in body composition changes by physical function status among middle-aged and older adults with type 2 diabetes mellitus and overweight/obesity participating in an intensive weight-loss intervention of diet and exercise over 12 months.

Methods

We conducted a secondary analysis of 12-month data from the Look AHEAD dual-energy X-ray absorptiometry substudy among participan

SUBMITTER: Chae K 

PROVIDER: S-EPMC12202034 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature