Impact of heart failure severity on the mortality benefit of mitral transcatheter edge-to-edge valve repair.

ABSTRACT:

Background

To assess the interaction between heart failure (HF) severity and optimal reduction of secondary mitral regurgitation (SMR) on mortality in patients undergoing transcatheter edge-to-edge repair (M-TEER).

Methods and results

Among 1656 patients included in the Italian Society of Interventional Cardiology (GIse) registry Of Transcatheter treatment of mitral valve regurgitaTiOn (GIOTTO) 984 had SMR and complete data on advanced HF. Advanced HF was defined as NYHA class III or IV, left ventricular ejection fraction ≤ 30%, and > 1 HF hospitalization during the last 12 months. Optimal M-TEER was defined as residual SMR ≤ 1 + at discharge. One hundred sixteen patients (11.8%) had advanced HF. Achievement of an optimal SMR reduction was similar in patients with and withou

SUBMITTER: Magni V 

PROVIDER: S-EPMC12202617 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature