Psychosocial burden of axial spondyloarthritis and impact of different disease domains: a systematic literature review.

ABSTRACT:

Objective

To assess the psychosocial impact of axial spondyloarthritis (axSpA).

Methods

A literature search was conducted in two stages: stage 1 included all patients with axSpA and stage 2 focused on patients with inadequate response to prior TNF inhibitor treatment. Selection criteria included population (adults with axSpA), outcomes of interest (psychosocial factors potentially impacted by axSpA, e.g. quality of life, mental health and work productivity) and context [disease-related (disease activity, pain) and -unrelated (gender, race, ethnicity, behaviour) factors potentially affecting psychosocial outcomes). Search results were categorized based on the core domains of disease activity, pain, morning stiffness, fatigue, physical function and overall functioning and heal

SUBMITTER: Poddubnyy D 

PROVIDER: S-EPMC12202762 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature