NIMBUS geometric clot extractor for challenging clots: Real-world clinical experience and clot composition.

ABSTRACT: PurposeRevascularization rates following mechanical thrombectomy (MT) for acute ischemic stroke (AIS) remain suboptimal for patients with fibrin-rich, recalcitrant clots. The NIMBUS Geometric Clot Extractor has demonstrated promising in vitro revascularization rates using fibrin-rich clot analogs. This study assessed the retrieval rate and composition of clot using NIMBUS in a clinical setting.MethodsThis retrospective study included patients who underwent MT with NIMBUS at two high-volume stroke centers between December 2019 and May 2021. NIMBUS was used for clots deemed challenging to remove at the interventionalist's discretion. At one of the centers, per pass clot was collected for histological analysis by an independent lab.ResultsA total of 37 patients (mean age 76.87 ± 11.73

SUBMITTER: Nordmeyer H 

PROVIDER: S-EPMC12202893 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature