Barriers and facilitators for implementing a pharmacogenetic passport: lessons learned from reusing sequencing data.

ABSTRACT:

Background

Pharmacogenetics uses individuals' genetic profiles to optimize drug treatment and prevent adverse reactions. One strategy to obtain information on pharmacogenes is to reuse sequencing data for a pharmacogenetic passport, providing information preemptively to healthcare professionals for utilization throughout a patient's lifetime.

Aim

To explore stakeholders' perceived barriers and facilitators and future perspectives of implementing a pharmacogenetic passport based on experiences from reusing sequencing data, in a Dutch University Medical Center.

Methods

Semi-structured interviews were conducted among 21 stakeholders. Interviews were analyzed using thematic analysis, and themes were grouped under the constructs of structure, culture, and practice.

Resu

SUBMITTER: Roelofsen AHA 

PROVIDER: S-EPMC12203843 | biostudies-literature | 2025 Apr-Apr

REPOSITORIES: biostudies-literature