Temperature-dependence of membrane protein-lipid interactions in membranes.

ABSTRACT: Membrane protein-lipid interactions, like other biomolecular interactions, are often temperature-sensitive. Here, we use variable-temperature electrospray ionization mass spectrometry to investigate the temperature dependence of protein-lipids interactions from membranes. The findings reveal that specific lipid binding, and in some cases metal ion binding, to membrane proteins is significantly enhanced at elevated temperatures.

SUBMITTER: Kumar S 

PROVIDER: S-EPMC12204147 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature