Superior aortic strain and ventriculoarterial coupling in older women are moderately correlated with Framingham 10-year risk.

ABSTRACT:

Aims

Traditional risk factors do not fully characterize cardiovascular aging and are less helpful in assessing sex differences in cardiovascular risk. Using a novel cardiovascular magnetic resonance (CMR) method, we determined sex differences in aortic global longitudinal strain (AOGLS) and ventriculoarterial coupling (VAC) with correlations to Framingham risk scores.

Methods and results

Community older adults without cardiovascular disease underwent CMR. AOGLS was the maximal absolute Lagrangian strain between the brachiocephalic artery and aortic annulus. VAC was aortic pulse wave velocity (AAPWV) divided by LVGLS. Among 202 participants (46.0% female, 70.2 ± 8.8 years), women had lower diastolic blood pressure (DBP) (70.5 ± 10.8 mmHg vs. 78.1 ± 9.5 mmHg, P < 0.001)

SUBMITTER: Wong JJ 

PROVIDER: S-EPMC12204193 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature