SARS-CoV-2 antibody immunity across three continents: the West Africa, West Indies, West London Consortium.

ABSTRACT:

Background

The experience of the COVID-19 pandemic has differed across continents. We hypothesized that regional differences in SARS-CoV-2 immunity might explain this observation. We therefore established the WWW Consortium in Ghana, W Africa; Jamaica, W Indies; and W London. Here, we describe the extent to which antibody immunity differs between these geographic locations.

Methods

The WWW Consortium harmonises across the HERITAGE (Accra, Ghana), WINDFall (Kingston, Jamaica) and Legacy (London, UK) studies, establishing sharing frameworks for samples, metadata, and data; related permissions and oversight; and associated physical and cloud infrastructure. With centralised testing, we performed serological assessments across all three locations at two snapshots in 2024 (April

SUBMITTER: Greenwood D 

PROVIDER: S-EPMC12204446 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature