Resilience in advanced cancer patients who obtain a long-term response to immunotherapy or targeted therapy: an Ecological Momentary Assessment study.

ABSTRACT:

Background

Approximately half of advanced cancer patients with a long-term response to immuno- or targeted therapy (IT/TT) (ie, long-term responders (LTRs)) experience heightened distress due to persistent uncertainty.

Purpose

We aimed to study to what extent supportive factors (ie, illness acceptance, tolerance of uncertainty, mindfulness, social support, optimism, emotion regulation variability, and positive affect in general and prior to a stressor) predict micro-level resilience in response to unpleasant daily life events.

Methods

We conducted an observational cohort study with a baseline assessment of supportive factors, followed by Ecological Momentary Assessment with 8 assessments a day for 14 consecutive days. Resilience was operationalized as maintenance of l

SUBMITTER: Zwanenburg LC 

PROVIDER: S-EPMC12204756 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature