Microbes Matter: Exploring the Connection Between Infant Gut Microbiota and Bone Development.

ABSTRACT: Human milk, compared to milk formula, is considered the optimal source of nutrition for infants as it can shape offspring microbiome composition, which is necessary for the production of key biomolecules that aid in development of infant physiological systems. A variety of factors in human milk can influence infant microbiome composition. One such factor is the type of oligosaccharides present, which is determined in part by maternal secretor status and itself determined by expression of fucosyltransferase-2 (FUT2). The aim of this study was to investigate the effects of secretor or non-secretor human milk as well as infant milk formula on infant gut microbiome composition and whether these changes in microbiota impact bone development. Fecal microbiota transfer from infants fed human milk

SUBMITTER: Caviness P 

PROVIDER: S-EPMC12205023 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature