Oxygen supplementation in ambulatory patients with heart failure: a randomized proof-of-concept study.

ABSTRACT:

Aims

The aims of this study were to describe the short-term effects of oxygen therapy on the physiological response and symptoms during ambulation in patients with chronic heart failure (HF).

Methods and results

In this pilot, cross-over, randomized study, subjects with chronic HF underwent two 6-min walk tests (6MWTs) on the same day. They were randomized to either receive oxygen through a portable oxygen concentrator (POC ON) during the first test and no oxygen (POC OFF) during the second test, or vice versa. Endpoints included (i) peripheral oxygen saturation, (ii) heart rate, and (iii) modified BORG scale. A linear mixed model for repeated measures was used for comparisons. A total of 20 participants were included, aged 70 ± 10 years, with the mean left ventricular eject

SUBMITTER: Tremblay-Gravel M 

PROVIDER: S-EPMC12205361 | biostudies-literature | 2025 May

REPOSITORIES: biostudies-literature